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Department

Immunology
MUSKT

Preferred Sample Type

Muscle Specific Tyrosine Kinase (MUSKT)

Suitable Specimen Types

  • Serum
1 mL

Sample Preparation

Centrifuge and separate. 100 uL of serum is necessary to allow duplicate analyses to be carried out if required. Grossly haemolysed or lipaemic samples are unsuitable for this assay.

Turnaround Time

14 days

Sample Stability

Stable at 4C

Muscle Specific Tyrosine Kinase (MUSKT)

General Information

Muscle specific tyrosine kinase (MuSK) is a surface membrane enzyme that is essential in aggregating Acetylcholine receptor during the development of the neuromuscular junction. Antibodies to MuSK are a second-line test for patients with suspected Myasthenia Gravis when acetylcholine receptor antibodies are negative and clinical suspicion remains high.

Patient Preparation

None.

Reference Range

Qualitative test. Normal result would be negative.

Specifications

  • EQA Scheme?: No
  • EQA Status: No EQA scheme currently available.