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Biochemistry

Referred Work (102)

Blood Sciences - Biochemistry referred work. These tests are available via the standard electronic and paper request cards. Site specific processing will be detailed in the test information. These tests are referred to other laboratories for analysis.

Solihull Biochemistry Laboratory (2)

Solihull Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Solihull Hospital site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Heartlands Biochemistry Laboratory (26)

Heartlands Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Heartlands site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Good Hope Biochemistry Laboratory (2)

Good Hope Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Good Hope site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Bone specific ALP (bone marker/bone markers)

	Male	Female
5-6 yrs	36-86	34-88
6-7 yrs	32-78	31-76
7-8 yrs	31-80	29-78
8-9 yrs	30-75	26-76
9-10 yrs	28-74	30-79
10-11yrs	35-82	28-83
11-12 yrs	36-84	26-77
12-13 yrs	34-86	24-71
13-14 yrs	28-77	22-69
14-15 yrs	27-73	20-66
15-16 yrs	24-72	16-62
16-17 yrs	20-65	14-56
Adults	10-40	Pre-menopausal: 10-26
		Post-menopausal: 14-50

Source: referral laboratory (July 2014)

Referred Work Biochemistry

Bone specific ALP (bone marker/bone markers)

	Male	Female
5-6 yrs	36-86	34-88
6-7 yrs	32-78	31-76
7-8 yrs	31-80	29-78
8-9 yrs	30-75	26-76
9-10 yrs	28-74	30-79
10-11yrs	35-82	28-83
11-12 yrs	36-84	26-77
12-13 yrs	34-86	24-71
13-14 yrs	28-77	22-69
14-15 yrs	27-73	20-66
15-16 yrs	24-72	16-62
16-17 yrs	20-65	14-56
Adults	10-40	Pre-menopausal: 10-26
		Post-menopausal: 14-50

Source: referral laboratory (July 2014)

Referred Work Biochemistry

C-Peptide

cpep Non- diabetic hypoglycaemia

See Insulin entry

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/c-peptide/tab/test https://pinboard.in/u:duty_biochemist/t:hypoglycaemia/

C-Peptide (Urine)

Provided by referral laboratory

UCPCR <0.2 nmol/mmol: Severe insulin deficiency

UCPCR 0.2 -0.6 nmol/mmol: Intermediate insulin secretion

UCPCR >0.6 nmol/mmol: Substantial endogenous insulin secretion

C peptide ranges 2 1024x620

Biochemistry

C-Reactive Protein (CRP)

0-5 mg/L

(Source : Abbott Diagnostics)

Concentration of up to 5 mg/L exclude many acute inflammatory diseases, but do not specifically exclude inflammatory processes.

Values in excess of 100mg/L show acute bacterial infection or active inflammation.

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/crp/tab/test https://pinboard.in/u:duty_biochemist/t:inflammation/

Caeruloplasmin

0.2-0.6g/L

Source : Abbott Diagnostics

Referred Work Biochemistry

https://pinboard.in/u:duty_biochemist/t:Wilson/ http://www.labtestsonline.org.uk/understanding/analytes/caeruloplasmin/tab/test

Calcitonin

Females <5.5 ng/L
Males < 18.9 ng/L
(New reference range July 2006 - Diasorin assay)

Referred Work Biochemistry

https://pinboard.in/u:duty_biochemist/t:Calcitonin/

Calcium

Neonate (<4wks) 2.0-2.7 mmol/L

4wks-16yrs 2.2-2.7 mmol/L

Adult 2.2-2.6 mmol/L

(Source : Pathology Harmony Recommendations)

Biochemistry

https://pinboard.in/u:duty_biochemist/t:Calcium/

Calcium (Urine)

2.50 -7.50 mmol/24 hour

Biochemistry

http://www.medscape.com/viewarticle/732914 https://pinboard.in/u:duty_biochemist/t:Calcium/

Calprotectin (faecal)

Clinical Cut offs (New Guidance in place 16/07/2026)

Adults (Individuals 16 and over)

FCAL <100 ug/g : Not indicative of GI Inflammation. Consider IBS or alternative diagnoses.

FCAL 100-250 ug/g : Indeterminate. Suggest repeating in 2-4 weeks if clinical concern remains or relevant family history. NSAIDs/PPIs should be stopped 2 weeks prior to sample collection. If repeat result also indeterminate suggest referral.

FCAL >250 ug/g : Indicative of GI inflammation, suggest referral.

Paediatrics (children <16 years old)

FCAL <50 ug/g - Not indicative of GI Inflammation

FCAL 50-150 ug/g : No further action needed. Consider repeat if symptoms worsen.

FCAL 151-250 ug/g : Indeterminate. Suggest repeating in 4 weeks if clinical concern remains or relevant family history. NSAIDs/PPIs should be stopped 2 weeks prior to sample collection. If repeat result also indeterminate suggest referral.

FCAL >250 ug/g : Indicative of GI inflammation, although false positives can occur in patients with high BMI. Suggest referral.

Biochemistry

http://www.labtestsonline.org.uk/news/calprotectin100813/

Cancer Antigen 125 (CA 125)

Population Reference Range used historically at BHH < 30 kU/L.

Manufacturers reference data. Roche Diagnostics June 2006:

593 pre- and post-menopausal healthy females yielded a 95th centile value of 35 kU/L.
It is suggested that a value of > 35 kU/L indicates that disease may still be present when used in the context of detection of residual or recurrent ovarian carcinoma following first line treatment.